NATIONAL INSTITUTES OF HEALTH · Grants & Funding

NOTICE: This Funding Opportunity has been superseded by PAR-27-042, published 14 August 2026. Applications submitted in response to PAR-26-118 after the final receipt date of 5 June 2026 will be withdrawn without review. Program area priorities have changed; see the replacement announcement.

PAR-26-118: Genomic Data Science and Computational Genomics (R01 Clinical Trial Not Allowed)

Funding Opportunity Number	PAR-26-118
Issued by	National Human Genome Research Institute (NHGRI)
Release Date	22 October 2025
Expiration Date	6 June 2026
Award Ceiling	$499,000 direct costs per year; up to 5 years
Cost Sharing	Not required

Purpose

This Funding Opportunity Announcement invites R01 applications developing computational methods for the analysis and interpretation of genomic data, including machine learning approaches to regulatory sequence, three-dimensional chromatin organization, and the integration of multi-omic measurement. Applications developing open, reusable software and benchmarks for the genomics community are encouraged.

Scientific Areas of Interest

Sequence-to-function prediction and regulatory genomics.
Three-dimensional genome organization; Hi-C and related assays.
Methods for structural interpretation of nucleic acids.
Benchmarking and evaluation infrastructure for genomic machine learning.

Eligibility

Higher education institutions, non-profits, for-profits, and governments. No PI or institutional submission limits. Foreign components allowed.

Application Due Dates

Standard NIH dates apply: 5 February, 5 June, 5 October, through the expiration date.

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